Anticorps Recombinant de lapin anti-TREM-1/CD354

TREM-1/CD354 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

241279D10

N° de cat : 98154-1-RR

Synonymes

TREM1, TREM 1, CD354, 241279D10

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Galerie de données de validation

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  FC experiment of human peripheral blood leukocytes using 98154-1-RR

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human TREM-1/CD354 Rabbit Recombinant Antibody (98154-1-RR, Clone: 241279D10) or Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Human CD16. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

• 

  FC experiment of human peripheral blood leukocytes using 98154-1-RR

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human TREM-1/CD354 Rabbit Recombinant Antibody (98154-1-RR, Clone: 241279D10)(red) or Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed.

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  Affinity and Kinetic Characterization of 98154-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98154-1-RR against Human TREM-1/CD354 were performed. The affinity constant is 0.676 nM.

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Applications testées

• Résultats positifs en cytométrie: human peripheral blood leukocytes

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98154-1-RR cible TREM-1/CD354 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: triggering receptor expressed on myeloid cells 1
• Masse moléculaire calculée: 26kDa
• Numéro d’acquisition GenBank: NM_018643.5
• Symbole du gène: TREM1
• Identification du gène (NCBI): 54210
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

Triggering receptor expressed on myeloid cells 1 (TREM-1, also known as CD354) is a member of the immunoglobulin superfamily, which is expressed on neutrophils and monocytes. TREM1 plays a role in the innate immune system. TREM1 amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers.

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