Anticorps Polyclonal de lapin anti-TRIM36

TRIM36 Polyclonal Antibody for IHC, IF-P, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

IHC, IF-P, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 25913-1-PBS

Synonymes

E3 ubiquitin-protein ligase TRIM36, EC:2.3.2.27, RING-type E3 ubiquitin transferase TRIM36, RNF98, tripartite motif containing 36

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Galerie de données de validation

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  IHC staining of mouse testis using 25913-1-AP (same clone as 25913-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 25913-1-AP (TRIM36 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25913-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse testis using 25913-1-AP (same clone as 25913-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 25913-1-AP (TRIM36 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25913-1-PBS in a different storage buffer formulation.

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  IHC staining of rat testis using 25913-1-AP (same clone as 25913-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat testis tissue slide using 25913-1-AP (TRIM36 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25913-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat testis using 25913-1-AP (same clone as 25913-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat testis tissue slide using 25913-1-AP (TRIM36 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25913-1-PBS in a different storage buffer formulation.

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  IF Staining of mouse testis using 25913-1-AP (same clone as 25913-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse testis tissue using TRIM36 antibody (25913-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25913-1-PBS in a different storage buffer formulation.

• 

  IF Staining of mouse testis using 25913-1-AP (same clone as 25913-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse testis tissue using TRIM36 antibody (25913-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25913-1-PBS in a different storage buffer formulation.

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Informations sur le produit

25913-1-PBS cible TRIM36 dans les applications de IHC, IF-P, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TRIM36 Protéine recombinante Ag23240
• Nom complet: tripartite motif-containing 36
• Poids moléculaire observé: 83 kDa
• Numéro d’acquisition GenBank: BC130334
• Symbole du gène: TRIM36
• Identification du gène (NCBI): 55521
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TRIM36, a member of the tripartite motif (TRIM) family of RING-containing proteins, also known as Haprin, is a microtubule-associated E3 ubiquitin ligase that plays a role in cytoskeletal organization, which was first discovered for its abundance in testis and found to be implicated in the spermatozoa acrosome reaction (PMID: 35053362, 30944633). TRIM36 was reported as a novel androgen signaling target gene and is upregulated in prostate cancer (PMID: 29449534).

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