Anticorps Polyclonal de lapin anti-TRIM38

• Phare
• Validé par KD/KO

TRIM38 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 13405-1-PBS

Synonymes

---

Galerie de données de validation

• 

  WB analysis of human liver using 13405-1-AP (same clone as 13405-1-PBS)

  human liver tissue were subjected to SDS PAGE followed by western blot with 13405-1-AP (TRIM38 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human colon using 13405-1-AP (same clone as 13405-1-PBS)

  human colon tissue were subjected to SDS PAGE followed by western blot with 13405-1-AP (TRIM38 antibody) at dilution of 1:0 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HEK-293 using 13405-1-AP (same clone as 13405-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 13405-1-AP (TRIM38 antibody) at dilution of 1:0 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver using 13405-1-AP (same clone as 13405-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 13405-1-AP (TRIM38 antibody) at dilution of 1:100 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung cancer using 13405-1-AP (same clone as 13405-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 13405-1-AP (TRIM38 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung cancer using 13405-1-AP (same clone as 13405-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 13405-1-AP (TRIM38 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver using 13405-1-AP (same clone as 13405-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 13405-1-AP (TRIM38 antibody) at dilution of 1:100 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.

• 

  IF Staining of L02 using 13405-1-AP (same clone as 13405-1-PBS)

  Immunofluorescent analysis of (-20℃ Ethanol) fixed L02 cells using 13405-1-AP (TRIM38 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

13405-1-PBS cible TRIM38 dans les applications de WB, IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TRIM38 Protéine recombinante Ag3840
• Nom complet: tripartite motif-containing 38
• Masse moléculaire calculée: 465 aa, 53 kDa
• Poids moléculaire observé: 53 kDa
• Numéro d’acquisition GenBank: BC026930
• Symbole du gène: TRIM38
• Identification du gène (NCBI): 10475
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The proinflammatory cytokines TNFα and IL-1β play central roles in many diseases, including infectious diseases, autoimmunity, and cancers. TRIM38 belongs to the TRIM protein family that is involved in various biological processes, including cell proliferation and apoptosis, innate immunity, and inflammatory response. It has been shown that TRIM38 acts as a suppressor in TOLL-like receptor (TLR)-mediated IFN-β induction by promoting degradation of TRAF6 and NAP1 through the ubiquitinproteasome system. (PMID:24434549)

{{ptg:RelatedPrimaryAntibodies}}