Anticorps Monoclonal anti-TRIM5

TRIM5 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1H1G9

N° de cat : 67492-1-PBS

Synonymes

1H1G9, EC:2.3.2.27, RING-type E3 ubiquitin transferase TRIM5, RNF88, tripartite motif containing 5

---

Galerie de données de validation

• 

  WB analysis using 67492-1-Ig (same clone as 67492-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67492-1-Ig (TRIM5 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67492-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

67492-1-PBS cible TRIM5 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2b
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: TRIM5 Protéine recombinante Ag30059
• Nom complet: tripartite motif-containing 5
• Masse moléculaire calculée: 493 aa, 56 kDa
• Poids moléculaire observé: 56 kDa
• Numéro d’acquisition GenBank: BC021258
• Symbole du gène: TRIM5
• Identification du gène (NCBI): 85363
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TRIM5 belongs to the large tripartite motif protein family, members of which typically are composed of 3 zinc-binding domains, a RING, unique B-box type 1 and B-box type 2 domains, followed by a coiled-coil (CC) region. TRIM proteins use homomultimerization to identify specific cell compartments. TRIM5 promotes innate immune signaling and that this activity is amplified by retroviral infection and interaction with the capsid lattice. TRIM5 has 6 variants termed alpha, beta, gamma, delta, epsilon, and iota with the MW of 56 kDa, 46 kDa, 40 kDa, 37 kDa, 31 kDa and 29 kDa. TRIM5 can form homodimers (~70 kDa) and homotrimers (90-160 kDa).

{{ptg:RelatedPrimaryAntibodies}}