Anticorps Polyclonal de lapin anti-TRIM58

• Phare
• Validé par KD/KO

TRIM58 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 28725-1-PBS

Synonymes

BIA2, Protein BIA2, TRIM, tripartite motif containing 58

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Galerie de données de validation

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  WB analysis using 28725-1-AP (same clone as 28725-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 28725-1-AP (TRIM58 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28725-1-PBS in a different storage buffer formulation.

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  WB analysis of PC-3 using 28725-1-AP (same clone as 28725-1-PBS)

  WB result of TRIM58 antibody (28725-1-AP; 1:2000; incubated at room temperature for 1.5 hours) with sh-Control and sh-TRIM58 transfected PC-3 cells. This data was developed using the same antibody clone with 28725-1-PBS in a different storage buffer formulation.

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Informations sur le produit

28725-1-PBS cible TRIM58 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TRIM58 Protéine recombinante Ag30014
• Nom complet: tripartite motif-containing 58
• Masse moléculaire calculée: 55 kDa
• Poids moléculaire observé: 55 kDa
• Numéro d’acquisition GenBank: NM_015431
• Symbole du gène: TRIM58
• Identification du gène (NCBI): 25893
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TRIM58 (Tripartite motif-containing protein 58) is an E3 ubiquitin ligase induced during late erythropoiesis. It can directly bind and ubiquitinate the intermediate chain of the microtubule motor dynein (DYNC1LI1/DYNC1LI2), stimulating the degradation of the dynein holoprotein complex. May participate in the erythroblast enucleation process through regulation of nuclear polarization (PMID: 25241935).

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