Anticorps Polyclonal de lapin anti-TRIM61

TRIM61 Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 24371-1-PBS

Synonymes

tripartite motif containing 61, TRIM, RNF35, RING finger protein 35

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Galerie de données de validation

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  IHC staining of mouse liver using 24371-1-AP (same clone as 24371-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 24371-1-AP (TRIM61 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24371-1-PBS in a different storage buffer formulation.

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  IF Staining of U2OS using 24371-1-AP (same clone as 24371-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed U2OS cells using TRIM61 antibody (24371-1-AP) at dilution of 1:200 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 24371-1-PBS in a different storage buffer formulation.

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Informations sur le produit

24371-1-PBS cible TRIM61 dans les applications de IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TRIM61 Protéine recombinante Ag21656
• Nom complet: tripartite motif-containing 61
• Masse moléculaire calculée: 209 aa, 24 kDa
• Numéro d’acquisition GenBank: BC089393
• Symbole du gène: TRIM61
• Identification du gène (NCBI): 391712
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TRIM61 is a member of the tripartite motif (TRIM) protein family. The RING domain in TRIM proteins, including TRIM61, can mediate the conjugation of proteins with ubiquitin, small ubiquitin-like modifier (SUMO), or the ubiquitin-like molecule IFN-stimulated protein of 15 kDa (ISG15), contributing to the biological flexibility of TRIM proteins. The E3 ligase activity of TRIM proteins, such as TRIM61, is essential for their role in post-translational modification, which plays a crucial role in cellular processes often resulting in targeted degradation of conjugated proteins.

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