Anticorps Recombinant de lapin anti-TRIM63

TRIM63 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242055A4

N° de cat : 82345-4-PBS

Synonymes

MuRF1, MuRF 1, Iris RING finger protein, IRF, EC:2.3.2.27

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Galerie de données de validation

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  WB analysis using 82345-4-RR (same clone as 82345-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 82345-4-RR (TRIM63 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82345-4-PBS in a different storage buffer formulation.

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Informations sur le produit

82345-4-PBS cible TRIM63 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: tripartite motif-containing 63
• Masse moléculaire calculée: 40 kDa
• Poids moléculaire observé: 40 kDa
• Numéro d’acquisition GenBank: NM_032588
• Symbole du gène: TRIM63
• Identification du gène (NCBI): 84676
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TRIM63, also named as IRF, MURF1, RNF28 and SMRZ, is E3 ubiquitin ligase. It is regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. TRIM63 may play a role in striated muscle atrophy and hypertrophy by regulating an anti-hypertrophic PKC-mediated signaling pathway. It may regulate the organization of myofibrils through TTN in muscle cells. TRIM63 is in muscle-specific expression.

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