Anticorps Polyclonal de lapin anti-TRIML2

TRIML2 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31976-1-PBS

Synonymes

EC:2.3.2.27, Probable E3 ubiquitin-protein ligase TRIML2, RING-type E3 ubiquitin transferase TRIML2, SPRY domain-containing protein 6, SPRYD6

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Galerie de données de validation

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  WB analysis using 31976-1-AP (same clone as 31976-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31976-1-AP (TRIML2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31976-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse testis using 31976-1-AP (same clone as 31976-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 31976-1-AP (TRIML2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31976-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31976-1-PBS cible TRIML2 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TRIML2 Protéine recombinante Ag37106
• Nom complet: tripartite motif family-like 2
• Masse moléculaire calculée: 50 kDa
• Poids moléculaire observé: 50 kDa
• Numéro d’acquisition GenBank: BC111959
• Symbole du gène: TRIML2
• Identification du gène (NCBI): 205860
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Tripartite motif family like 2 (TRIML2, also known as SPRYD6) is a member of the tripartite motif (TRIM) family of proteins. It probably interacts with p53 to facilitate the modification of p53 with small ubiquitin-like modifier 2 (SUMO2) (PMID: 25256710). By regulating p53, TRIML2 may also be an important factor in the pathogenesis of Alzheimer's disease (PMID: 27471163).

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