Anticorps Polyclonal de lapin anti-TRPA1

TRPA1 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

N° de cat : 25226-1-AP

Synonymes

Wasabi receptor, p120, ANKTM1

---

Galerie de données de validation

• 

  WB analysis using 25226-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 25226-1-AP (TRPA1 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours.

---

Applications testées

• Résultats positifs en WB: cellules A549, cellules U2OS

Dilution recommandée

• Western Blot (WB): WB : 1:1000-1:8000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

25226-1-AP cible TRPA1 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TRPA1 Protéine recombinante Ag18685
• Nom complet: transient receptor potential cation channel, subfamily A, member 1
• Masse moléculaire calculée: 1119 aa, 128 kDa
• Poids moléculaire observé: 130 kDa
• Numéro d’acquisition GenBank: BC153003
• Symbole du gène: TRPA1
• Identification du gène (NCBI): 8989
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

TRPA1 (Transient Receptor Potential Ankyrin 1) is a member of the transient receptor potential (TRP) channel family and is a non-selective cation channel. TRPA1 is predominantly expressed in sensory neurons and is involved in a variety of physiological activities, such as stabilizing cellular membrane potentials, maintaining cellular fluid homeostasis, and regulating intercellular signaling. TRPA1 is a multimodal cell membrane receptor that senses different stimuli and upon activation generates action potential signals via osmolality, temperature and inflammatory factors. TRPA1 has been associated with neurogenic inflammation, osteoarthritis, atopic dermatitis, asthma, inflammatory bowel disease, migraine headache, cancer pain, gout and other diseases, and it is a promising target for drug therapy.

{{ptg:RelatedPrimaryAntibodies}}