Anticorps Recombinant de lapin anti-TRPC3

TRPC3 Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241075H3

N° de cat : 84019-5-PBS

Synonymes

Transient receptor protein 3, Short transient receptor potential channel 3, hTrp-3, hTrp3, hTrp 3

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Galerie de données de validation

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  WB analysis using 84019-5-RR (same clone as 84019-5-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84019-5-RR (TRPC3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84019-5-PBS in a different storage buffer formulation.

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  WB analysis of HEK-293 using 84019-5-RR (same clone as 84019-5-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 84019-5-RR (TRPC3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84019-5-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP00972-1

  Cytometric bead array standard curve of MP00972-1, TRPC3 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84019-5-PBS. Detection antibody: 84019-4-PBS. Standard: Ag13024. Range: 0.781-100 ng/mL.

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Informations sur le produit

84019-5-PBS cible TRPC3 dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: TRPC3 Protéine recombinante Ag13024
• Nom complet: transient receptor potential cation channel, subfamily C, member 3
• Masse moléculaire calculée: 848 aa, 97 kDa
• Poids moléculaire observé: 105 kDa, 97 kDa
• Numéro d’acquisition GenBank: BC093682
• Symbole du gène: TRPC3
• Identification du gène (NCBI): 7222
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TRPC3 (Short transient receptor potential channel 3), also known as TRP3. It is expected to be located in the cell membrane, which is expressed predominantly in brain and at much lower levels in ovary, colon, small intestine, lung, prostate, placenta and testis. TRPC3 is one of the classical members of the mammalian transient receptor potential (TRP) superfamily of ion channels. TRPC3 is a molecule with intriguing sensory features including the direct recognition of and activation by diacylglycerols (DAG). Although TRPC3 channels are ubiquitously expressed, they appear to control functions of the cardiovascular system and the brain in a highly specific manner. Moreover, a role of TRPC3 in immunity, cancer, and tissue remodeling has been proposed, generating much interest in TRPC3 as a target for pharmacological intervention. The molecular weight of TRPC3 is 105 kDa, and it can recognize another isoform. (PMID: 30037143)

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