Anticorps Recombinant de lapin anti-TRPC3

TRPC3 Recombinant Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

241075H3

N° de cat : 84019-5-RR

Synonymes

Transient receptor protein 3, Short transient receptor potential channel 3, hTrp-3, hTrp3, hTrp 3

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Galerie de données de validation

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  WB analysis using 84019-5-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 84019-5-RR (TRPC3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

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  WB analysis of HEK-293 using 84019-5-RR

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 84019-5-RR (TRPC3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: tissu de cervelet de souris, cellules HEK-293

Dilution recommandée

• Western Blot (WB): WB : 1:2000-1:10000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

84019-5-RR cible TRPC3 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: TRPC3 Protéine recombinante Ag13024
• Nom complet: transient receptor potential cation channel, subfamily C, member 3
• Masse moléculaire calculée: 848 aa, 97 kDa
• Poids moléculaire observé: 105 kDa, 97 kDa
• Numéro d’acquisition GenBank: BC093682
• Symbole du gène: TRPC3
• Identification du gène (NCBI): 7222
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

TRPC3 (Short transient receptor potential channel 3), also known as TRP3. It is expected to be located in the cell membrane, which is expressed predominantly in brain and at much lower levels in ovary, colon, small intestine, lung, prostate, placenta and testis. TRPC3 is one of the classical members of the mammalian transient receptor potential (TRP) superfamily of ion channels. TRPC3 is a molecule with intriguing sensory features including the direct recognition of and activation by diacylglycerols (DAG). Although TRPC3 channels are ubiquitously expressed, they appear to control functions of the cardiovascular system and the brain in a highly specific manner. Moreover, a role of TRPC3 in immunity, cancer, and tissue remodeling has been proposed, generating much interest in TRPC3 as a target for pharmacological intervention. The molecular weight of TRPC3 is 105 kDa, and it can recognize another isoform. (PMID: 30037143)

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