Anticorps Recombinant de lapin anti-TRPM7

TRPM7 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241191G7

N° de cat : 84324-1-PBS

Synonymes

EC:2.7.11.1, Channel-kinase 1, Channel kinase 1, CHAK1, CHAK

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Galerie de données de validation

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  WB analysis using 84324-1-RR (same clone as 84324-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84324-1-RR (TRPM7 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84324-1-PBS in a different storage buffer formulation.

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Informations sur le produit

84324-1-PBS cible TRPM7 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: transient receptor potential cation channel, subfamily M, member 7
• Masse moléculaire calculée: 213 kDa
• Poids moléculaire observé: 220 kDa
• Numéro d’acquisition GenBank: NM_017672
• Symbole du gène: TRPM7
• Identification du gène (NCBI): 54822
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Transient receptor potential melastatin 7 (TRPM7), along with the closely related TRPM6, are unique channels that have dual operations: cation permeability and kinase activity. In contrast to the limited tissue distribution of TRPM6, TRPM7 is widely expressed among tissues and is therefore implicated in a variety of cellular functions physiologically and pathophysiologically. The discovery of TRPM7's unique structure imparting dual ion channel and kinase activities shed light onto novel and peculiar biological functions, such as Mg2+ homeostasis, cellular Ca2+ flickering, and even intranuclear transcriptional regulation by a cleaved kinase domain translocated to nuclei.

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