Anticorps Polyclonal de lapin anti-TRPM8

TRPM8 Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 12813-1-PBS

Synonymes

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Galerie de données de validation

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  IHC staining of human liver cancer using 12813-1-AP (same clone as 12813-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 12813-1-AP (TRPM8 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12813-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 12813-1-AP (same clone as 12813-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 12813-1-AP (TRPM8 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12813-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 12813-1-AP (same clone as 12813-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 12813-1-AP (TRPM8 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12813-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 12813-1-AP (same clone as 12813-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 12813-1-AP (TRPM8 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12813-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human prostate cancer using 12813-1-AP (same clone as 12813-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 12813-1-AP (TRPM8 antibody) at dilution of 1:100 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12813-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human prostate cancer using 12813-1-AP (same clone as 12813-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 12813-1-AP (TRPM8 antibody) at dilution of 1:100 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12813-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon cancer using 12813-1-AP (same clone as 12813-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 12813-1-AP (TRPM8 antibody) at dilution of 1:100 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12813-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human colon cancer using 12813-1-AP (same clone as 12813-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 12813-1-AP (TRPM8 antibody) at dilution of 1:100 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12813-1-PBS in a different storage buffer formulation.

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  IF Staining of SH-SY5Y using 12813-1-AP (same clone as 12813-1-PBS)

  Immunofluorescent analysis of SH-SY5Y cells using 12813-1-AP (TRPM8 antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG. This data was developed using the same antibody clone with 12813-1-PBS in a different storage buffer formulation.

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Informations sur le produit

12813-1-PBS cible TRPM8 dans les applications de IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TRPM8 Protéine recombinante Ag3483
• Nom complet: transient receptor potential cation channel, subfamily M, member 8
• Masse moléculaire calculée: 1104 aa, 128 kDa
• Numéro d’acquisition GenBank: BC001135
• Symbole du gène: TRPM8
• Identification du gène (NCBI): 79054
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TRPM8, also known as CMR1 (cold-menthol receptor-1), is a nonselective cation channel activated by cold and the cooling substances menthol and icilin (PMID: 11893340; 11882888). It serves as a neuronal sensor of cold temperatures. Functioning TRPM8 channels are required for behavioral responses to innocuous cool, noxious cold, injury-evoked cold hypersensitivity, and cooling-mediated analgesia (PMID: 17538622; 21438154; 16920620; 21984952). Additionally, TRPM8 has also been reported to be involved in thermoregulation and the regulation of basal tear flow (PMID: 21407809; 21076394). TRPM8 is expressed extensively in sensory nerves, human prostate and overexpressed in a variety of cancers including prostate, breast, lung, colon and skin melanomas (PMID: 11325849; 20816009).

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