Anticorps Polyclonal de lapin anti-TRPV6

TRPV6 Polyclonal Antibody for WB, IF/ICC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IF/ICC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 13411-1-PBS

Synonymes

CATL, CaT1, CaT like, CaT L, Calcium transport protein 1

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Galerie de données de validation

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  WB analysis of human placenta using 13411-1-AP (same clone as 13411-1-PBS)

  human placenta tissue were subjected to SDS PAGE followed by western blot with 13411-1-AP (TRPV6 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13411-1-PBS in a different storage buffer formulation.

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  WB analysis of human placenta using 13411-1-AP (same clone as 13411-1-PBS)

  human placenta tissue were subjected to SDS PAGE followed by western blot with 13411-1-AP (TRPV6 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13411-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse kidney using 13411-1-AP (same clone as 13411-1-PBS)

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 13411-1-AP (TRPV6 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13411-1-PBS in a different storage buffer formulation.

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  WB analysis of PC-3 using 13411-1-AP (same clone as 13411-1-PBS)

  PC-3 cells were subjected to SDS PAGE followed by western blot with 13411-1-AP (TRPV6 antibody) at dilution of 1:0 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13411-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse kidney using 13411-1-AP (same clone as 13411-1-PBS)

  IP result of anti-TRPV6 (IP:13411-1-AP, 4ug; Detection:13411-1-AP 1:300) with mouse kidney tissue lysate 4000ug. This data was developed using the same antibody clone with 13411-1-PBS in a different storage buffer formulation.

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  IF Staining of HeLa using 13411-1-AP (same clone as 13411-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using TRPV6 antibody (13411-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 13411-1-PBS in a different storage buffer formulation.

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Informations sur le produit

13411-1-PBS cible TRPV6 dans les applications de WB, IF/ICC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TRPV6 Protéine recombinante Ag4060
• Nom complet: transient receptor potential cation channel, subfamily V, member 6
• Masse moléculaire calculée: 725 aa, 83 kDa
• Poids moléculaire observé: 83 kDa, 70 kDa
• Numéro d’acquisition GenBank: BC034814
• Symbole du gène: TRPV6
• Identification du gène (NCBI): 55503
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TRPV6, also named as CAT1 or ECaC2, is a member of the transient receptor potential (TRP) family of membrane proteins. Unlike most TRP channels, TRPV6 and its closest relative, TRPV5, are calcium-selective channels. TRPV6 is highly expressed in the proximal intestine, placenta and exocrine tissues (PMID: 12869611). It is probably involved in calcium absorption in various tissues, including calcium reabsorption in kidney. TRPV6 is overexpressed in some cancers and exhibits oncogenic potential.

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