Anticorps Polyclonal de lapin anti-TRPV6

TRPV6 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31045-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 31045-1-AP (same clone as 31045-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31045-1-AP (TRPV6 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31045-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31045-1-PBS cible TRPV6 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TRPV6 Protéine recombinante Ag34052
• Nom complet: transient receptor potential cation channel, subfamily V, member 6
• Masse moléculaire calculée: 87KD
• Poids moléculaire observé: 75 kDa
• Numéro d’acquisition GenBank: NM_018646
• Symbole du gène: TRPV6
• Identification du gène (NCBI): 55503
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TRPV6, also named as CAT1 or ECaC2, is a member of the transient receptor potential (TRP) family of membrane proteins. Unlike most TRP channels, TRPV6 and its closest relative, TRPV5, are calcium-selective channels. TRPV6 is highly expressed in the proximal intestine, placenta and exocrine tissues (PMID: 12869611). It is probably involved in calcium absorption in various tissues, including calcium reabsorption in kidney. TRPV6 is overexpressed in some cancers and exhibits oncogenic potential.

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