Anticorps Polyclonal de lapin anti-TSPAN2

TSPAN2 Polyclonal Antibody for WB, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 20463-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 20463-1-AP (same clone as 20463-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 20463-1-AP (TSPAN2 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20463-1-PBS in a different storage buffer formulation.

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  WB analysis of HL-60 using 20463-1-AP (same clone as 20463-1-PBS)

  HL-60 cells were subjected to SDS PAGE followed by western blot with 20463-1-AP (TSPAN2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20463-1-PBS in a different storage buffer formulation.

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  IP experiment of HL-60 using 20463-1-AP (same clone as 20463-1-PBS)

  IP result of anti-TSPAN2 (IP:20463-1-AP, 4ug; Detection:20463-1-AP 1:500) with HL-60 cells lysate 960ug. This data was developed using the same antibody clone with 20463-1-PBS in a different storage buffer formulation.

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Informations sur le produit

20463-1-PBS cible TSPAN2 dans les applications de WB, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TSPAN2 Protéine recombinante Ag14299
• Nom complet: tetraspanin 2
• Masse moléculaire calculée: 221 aa, 24 kDa
• Poids moléculaire observé: 30-35 kDa
• Numéro d’acquisition GenBank: BC021675
• Symbole du gène: TSPAN2
• Identification du gène (NCBI): 10100
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TSPAN2 is a membrane protein of the tetraspanin superfamily, which are characterized by the presence of four conserved transmembrane regions. Tetraspanins have been involved in diverse processes such as cell activation and proliferation, adhesion and motility, differentiation, and cancer. It has been reported that TSPAN2 is involved in cell invasion and motility during lung cancer progression (PMID: 24726368). TSPAN2 enhances cell motility and invasiveness by assisting CD44 in scavenging intracellular reactive oxygen species.

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