Anticorps Polyclonal de lapin anti-TSPAN6

TSPAN6 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, ELISA

Conjugaison

Non conjugué

Publications(2)

N° de cat : 12293-1-AP

Synonymes

A15 homolog, T245, T245 protein, tetraspanin 6, Tetraspanin TM4 D, TM4SF6, TSPAN 6, TSPAN6

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Galerie de données de validation

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  WB analysis of mouse colon using 12293-1-AP

  mouse colon tissue were subjected to SDS PAGE followed by western blot with 12293-1-AP (TSPAN6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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  WB analysis using 12293-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 12293-1-AP (TSPAN6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: tissu de côlon de souris, tissu de côlon de rat

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• WB: See 2 publications below

Informations sur le produit

12293-1-AP cible TSPAN6 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Réactivité citée: rat, Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TSPAN6 Protéine recombinante Ag2964
• Nom complet: tetraspanin 6
• Masse moléculaire calculée: 245 aa, 28 kDa
• Poids moléculaire observé: 25-30 kDa
• Numéro d’acquisition GenBank: BC012389
• Symbole du gène: TSPAN6
• Identification du gène (NCBI): 7105
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

TSPAN6 (also known as TM4SF6) is a membrane protein of the tetraspanin superfamily, which are characterized by the presence of four conserved transmembrane regions. Tetraspanins have been involved in diverse processes such as cell activation and proliferation, adhesion and motility, differentiation, and cancer. TSPAN6 gene is widely expressed, with high mRNA levels in liver, pancreas, kidney, and ovary (PMID: 9782095). TSPAN6 has been reported as a negative regulator of the RLR pathway by interacting with MAVS in a ubiquitination-dependent manner (PMID: 22908223).

Publications

Species	Application	Title
rat	WB	Stem Cell Res Ther; Research on the TSPAN6 regulating the secretion of ADSCs-Exos through syntenin-1 and promoting wound healing; Authors - Zhihua Qiao
human	WB	Eur J Med Res; Diagnostic and prognostic significance of tetraspanin 6 and its role in facilitating glioma progression; Authors - Longqi Sa

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