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Anticorps Recombinant de lapin anti-CFAP70

CFAP70 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241177C9

N° de cat : 84133-5-PBS

Synonymes

241177C9, TPR repeat protein 18, TTC18

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using CFAP70 Recombinant antibody (84133-5-RR)

    WB analysis using 84133-5-RR (same clone as 84133-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84133-5-RR (TTC18 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84133-5-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84133-5-RR

    Affinity and Kinetic Characterization of 84133-5-RR

    Biolayer interferometry (BLl) kinetic assays of 84133-5-RR against Human TTC18 were performed. The affinity constant is 5.06 nM.

Informations sur le produit

84133-5-PBS cible CFAP70 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène CFAP70 Protéine recombinante Ag35209
Nom complet tetratricopeptide repeat domain 18
Masse moléculaire calculée126 kDa
Poids moléculaire observé110 kDa, 128 kDa
Numéro d’acquisition GenBankBC032856
Symbole du gène TTC18
Identification du gène (NCBI) 118491
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Protein A purfication
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Cilia- and flagella-associated protein 70 (CFAP70), also known as TTC18, harbours eight tetratricopeptide repeats (TPRs) and bound tightly to the ciliary axoneme. CFAP70 is necessary to assemble spermatid flagella and could be used as a diagnostic target for male infertility with OAT in the clinic.CFAP70 is a novel regulatory component of the ODA in motile cilia and flagella, and that the N-terminus is important for its ciliary localization (PMID: 30158508).

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