Anticorps Polyclonal de lapin anti-TTC7B

TTC7B Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 25713-1-PBS

Synonymes

c14_5685, Tetratricopeptide repeat protein 7-like-1, TPR repeat protein 7 like 1, TPR repeat protein 7B, TPR repeat protein 7-like-1

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Galerie de données de validation

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  WB analysis of mouse brain using 25713-1-AP (same clone as 25713-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 25713-1-AP (TTC7B antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25713-1-PBS in a different storage buffer formulation.

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  IP experiment of K-562 using 25713-1-AP (same clone as 25713-1-PBS)

  IP result of anti-TTC7B (IP:25713-1-AP, 4ug; Detection:25713-1-AP 1:600) with K-562 cells lysate 1640 ug. This data was developed using the same antibody clone with 25713-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse liver using 25713-1-AP (same clone as 25713-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 25713-1-AP (TTC7B antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25713-1-PBS in a different storage buffer formulation.

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Informations sur le produit

25713-1-PBS cible TTC7B dans les applications de WB, IHC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TTC7B Protéine recombinante Ag22388
• Nom complet: tetratricopeptide repeat domain 7B
• Masse moléculaire calculée: 843 aa, 94 kDa
• Poids moléculaire observé: 50-53 kDa
• Numéro d’acquisition GenBank: BC153122
• Symbole du gène: TTC7B
• Identification du gène (NCBI): 145567
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TTC7B (Tetratricopeptide Repeat Domain 7B) is a protein-coding gene belonging to the tetratricopeptide repeat (TPR) family, which plays critical roles in cellular signaling, membrane dynamics, and disease pathogenesis. TTC7B is associated with focal adhesion (FA) disassembly and cell migration, promoting tumor invasion and metastasis. Its expression is tied to FA-related pathways like the PINCH-ILK-PARVIN complex (PMID: 37990988).

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