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Anticorps Recombinant de lapin anti-TTLL12

TTLL12 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241904F4

N° de cat : 84493-6-PBS

Synonymes

Tubulin--tyrosine ligase-like protein 12, Inactive tubulin--tyrosine ligase-like protein 12, 241904F4

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using TTLL12 Recombinant antibody (84493-6-RR)

    WB analysis using 84493-6-RR (same clone as 84493-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84493-6-RR (TTLL12 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84493-6-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84493-6-RR

    Affinity and Kinetic Characterization of 84493-6-RR

    Biolayer interferometry (BLl) kinetic assays of 84493-6-RR against Human TTLL12 were performed. The affinity constant is 57.3 pM.

Informations sur le produit

84493-6-PBS cible TTLL12 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène TTLL12 Protéine recombinante Ag13804
Nom complet tubulin tyrosine ligase-like family, member 12
Masse moléculaire calculée 644 aa, 74 kDa
Poids moléculaire observé 75 kDa
Numéro d’acquisition GenBankBC001070
Symbole du gène TTLL12
Identification du gène (NCBI) 23170
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Protein A purfication
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TTLL12 is a member of the tubulin tyrosine ligase (TTL) family that is highly conserved in phylogeny. TTLL12 contains 644 amino acids and has a SET-like domain and a TTL-like domain. TTLL12 is involved in the regulation of tubulin and histone modification and is a negative regulator of RNA virus-induced type I interferon. During the cell cycle, Both trimethylation of H4K20 and tubulin detyrosination levels were altered by TTLL2 expression (PMID: 23251473).

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