Anticorps Polyclonal de lapin anti-TWEAKR/CD266

TWEAKR/CD266 Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 19836-1-PBS

Synonymes

CD266, TNFRSF12A, TweakR, FGF-inducible 14, FGF inducible 14

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Galerie de données de validation

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  IHC staining of mouse heart using 19836-1-AP (same clone as 19836-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 19836-1-AP (TWEAKR antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19836-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse heart using 19836-1-AP (same clone as 19836-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 19836-1-AP (TWEAKR antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19836-1-PBS in a different storage buffer formulation.

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Informations sur le produit

19836-1-PBS cible TWEAKR/CD266 dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: TWEAKR/CD266 Protéine recombinante Ag13823
• Nom complet: tumor necrosis factor receptor superfamily, member 12A
• Masse moléculaire calculée: 129 aa, 14 kDa
• Numéro d’acquisition GenBank: BC002718
• Symbole du gène: TWEAKR
• Identification du gène (NCBI): 51330
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TWEAKR (also known as CD266, FN14, TNFRSF12A) is a member of the TNF receptor superfamily which is activated by its ligand, the cytokine TWEAK (TNFSF12). TWEAKR is the smallest member of the TNFR superfamily. TweakR was first described as an FGF-inducible gene that played a role in fibroblast adhesion and migration. Subsequently, the induction of TweakR expression by other growth factors and/or upon tissue injury was observed in multiple cell types, including hepatocytes, endothelial cells, adipocytes, and cardiomyocytes. (PMID: 23073510, PMID: 24409185)

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