Anticorps Recombinant de lapin anti-TWEAKR/CD266

TWEAKR/CD266 Recombinant Antibody for Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

240991C5

N° de cat : 83916-2-PBS

Synonymes

CD266, TNFRSF12A, TweakR, FGF inducible 14, DR3LG

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Galerie de données de validation

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  Cytometric bead array standard curve of MP00861-1

  Cytometric bead array standard curve of MP00861-1, TWEAKR/CD266 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 83916-1-PBS. Detection antibody: 83916-2-PBS. Standard: Ag13823. Range: 0.78-100 ng/mL.

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  Affinity and Kinetic Characterization of 83916-2-PBS

  Biolayer interferometry (BLl) kinetic assay of 83916-2-PBS against Human TWEAKR/CD266 was performed. The affinity constant is 0.884 nM.

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Informations sur le produit

83916-2-PBS cible TWEAKR/CD266 dans les applications de Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: TWEAKR/CD266 Protéine recombinante Ag13823
• Nom complet: tumor necrosis factor receptor superfamily, member 12A
• Masse moléculaire calculée: 129 aa, 14 kDa
• Numéro d’acquisition GenBank: BC002718
• Symbole du gène: TWEAKR
• Identification du gène (NCBI): 51330
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

TWEAKR (also known as CD266, FN14, TNFRSF12A) is a member of the TNF receptor superfamily which is activated by its ligand, the cytokine TWEAK (TNFSF12). TWEAKR is the smallest member of the TNFR superfamily. TweakR was first described as an FGF-inducible gene that played a role in fibroblast adhesion and migration. Subsequently, the induction of TweakR expression by other growth factors and/or upon tissue injury was observed in multiple cell types, including hepatocytes, endothelial cells, adipocytes, and cardiomyocytes. (PMID: 23073510, PMID: 24409185)

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