Anticorps Recombinant de lapin anti-TWEAKR/CD266

TWEAKR/CD266 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

CoraLite®594 Fluorescent Dye

CloneNo.

240991C5

N° de cat : CL594-98125

Synonymes

CD266, TNFRSF12A, TweakR, 240991C5, APO3L

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Galerie de données de validation

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  FC experiment of HT-1080 using CL594-98125

  1x10^6 HT-1080 cells were surface stained with 5 ul CoraLite®594 Anti-Human TWEAKR/CD266 Rabbit RecAb (CL594-98125, Clone:240991C5) (red) or 5 ul CoraLite®594 Rabbit IgG Isotype Control RecAb (CL594-98136, Clone: 240953C9) (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: cellules HT-1080,

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL594-98125 cible TWEAKR/CD266 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: TWEAKR/CD266 Protéine recombinante Ag13823
• Nom complet: tumor necrosis factor receptor superfamily, member 12A
• Masse moléculaire calculée: 129 aa, 14 kDa
• Numéro d’acquisition GenBank: BC002718
• Symbole du gène: TWEAKR
• Identification du gène (NCBI): 51330
• Conjugaison: CoraLite®594 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 588 nm / 604 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

TWEAKR (also known as CD266, FN14, TNFRSF12A) is a member of the TNF receptor superfamily which is activated by its ligand, the cytokine TWEAK (TNFSF12). TWEAKR is the smallest member of the TNFR superfamily. TWEAKR was first described as an FGF-inducible gene that played a role in fibroblast adhesion and migration. Subsequently, the induction of TWEAKR expression by other growth factors and/or upon tissue injury was observed in multiple cell types, including hepatocytes, endothelial cells, adipocytes, and cardiomyocytes. (PMID: 23073510, PMID: 24409185)

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