Anticorps Recombinant de lapin anti-TYRO3

TYRO3 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250330B12

N° de cat : 86404-3-PBS

Synonymes

Dtk, EC:2.7.10.1, Etk2/tyro3, Rse, Tif

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Galerie de données de validation

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  WB analysis using 86404-3-RR (same clone as 86404-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86404-3-RR (Tyro3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86404-3-PBS in a different storage buffer formulation.

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Informations sur le produit

86404-3-PBS cible TYRO3 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons rat, souris

• Réactivité: rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: TYRO3 Protéine recombinante Eg2918
• Nom complet: TYRO3 protein tyrosine kinase 3
• Masse moléculaire calculée: 96 kDa
• Poids moléculaire observé: 130 kDa
• Numéro d’acquisition GenBank: NM_019392.2
• Symbole du gène: Tyro3
• Identification du gène (NCBI): 22174
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

YRO3 has a structure includes a cytoplasmic domain and an extracellular ligand binding region. And ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. TYRO3 is associated with many physiological processes including cell survival, migration and differentiation. It has been reported that TYRO3 can be expressed in various regions of the mammalian central nervous system. The molecular mass of TYRO3 is 130 kDa, the apparent molecular mass is higher due to glycosylation.((PMID: 8873131, 23354874, 21539887)

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