Anticorps Polyclonal de lapin anti-Teneurin 1

Teneurin 1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 21696-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of H69/H146 cells using 21696-1-AP (same clone as 21696-1-PBS)

  WB result of anti-ODZ1 (21696-1-AP) with two cell lines by Dr. Petrini, Iacopo. This data was developed using the same antibody clone with 21696-1-PBS in a different storage buffer formulation.

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  WB analysis using 21696-1-AP (same clone as 21696-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 21696-1-AP (ODZ1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21696-1-PBS in a different storage buffer formulation.

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  WB analysis of human brain using 21696-1-AP (same clone as 21696-1-PBS)

  human brain tissue were subjected to SDS PAGE followed by western blot with 21696-1-AP (ODZ1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21696-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse brain using 21696-1-AP (same clone as 21696-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 21696-1-AP (ODZ1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21696-1-PBS in a different storage buffer formulation.

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  IHC staining of human brain using 21696-1-AP (same clone as 21696-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 21696-1-AP (ODZ1 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21696-1-PBS in a different storage buffer formulation.

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  IHC staining of human brain using 21696-1-AP (same clone as 21696-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 21696-1-AP (ODZ1 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21696-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 21696-1-AP (same clone as 21696-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 21696-1-AP (Teneurin 1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21696-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 21696-1-AP (same clone as 21696-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 21696-1-AP (Teneurin 1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21696-1-PBS in a different storage buffer formulation.

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Informations sur le produit

21696-1-PBS cible Teneurin 1 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Teneurin 1 Protéine recombinante Ag16289
• Nom complet: odz, odd Oz/ten-m homolog 1(Drosophila)
• Masse moléculaire calculée: 2732 aa, 306 kDa
• Poids moléculaire observé: 305 kDa
• Numéro d’acquisition GenBank: BC140783
• Symbole du gène: Teneurin 1
• Identification du gène (NCBI): 10178
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ODZ1 (also known as teneurin-1, TENM1), which plays a key role in central nervous system ontogenesis. ODZ1 is upregulated in Glioblastoma cells through a Stat3-mediated pathway activated by IL-6, which is released by tumor-associated monocytes. In addition, a hypoxic microenvironment regulates GBM tumor cell migration in part by inducing ODZ1 through hypomethylation of a CpG island in the ODZ1 promoter.

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