Anticorps Monoclonal anti-Thyroglobulin

Thyroglobulin Monoclonal Antibody for IHC, IF-P, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain

Applications

IHC, IF-P, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

4D3C5

N° de cat : 60272-1-PBS

Synonymes

TG, 4D3C5

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Galerie de données de validation

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  IHC staining of human thyroid using 60272-1-Ig (same clone as 60272-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human thyroid tissue slide using 60272-1-Ig (Thyroglobulin antibody at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 60272-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human thyroid using 60272-1-Ig (same clone as 60272-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human thyroid tissue slide using 60272-1-Ig (Thyroglobulin antibody at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 60272-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human thyroid cancer using 60272-1-Ig (same clone as 60272-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 60272-1-Ig (Thyroglobulin antibody at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 60272-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human thyroid cancer using 60272-1-Ig (same clone as 60272-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 60272-1-Ig (Thyroglobulin antibody at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 60272-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human thyroid cancer using 60272-1-Ig (same clone as 60272-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 60272-1-Ig (Thyroglobulin antibody at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60272-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human thyroid cancer using 60272-1-Ig (same clone as 60272-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 60272-1-Ig (Thyroglobulin antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60272-1-PBS in a different storage buffer formulation.

• 

  IF Staining of human thyroid cancer using 60272-1-Ig (same clone as 60272-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed human thyroid cancer tissue using Thyroglobulin antibody (60272-1-Ig, Clone: 4D3C5 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 60272-1-PBS in a different storage buffer formulation.

• 

  IF Staining of human thyroid cancer using 60272-1-Ig (same clone as 60272-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed human thyroid cancer tissue using Thyroglobulin antibody (60272-1-Ig, Clone: 4D3C5 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 60272-1-PBS in a different storage buffer formulation.

• 

  IF Staining of human thyroid cancer using 60272-1-Ig (same clone as 60272-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded human thyroid cancer tissue using Thyroglobulin antibody (60272-1-Ig, Clone: 4D3C5 ) at dilution of 1:400 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Mouse Recombinant Secondary Antibody (H+L) (RGAM002). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60272-1-PBS in a different storage buffer formulation.

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Informations sur le produit

60272-1-PBS cible Thyroglobulin dans les applications de IHC, IF-P, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Thyroglobulin Protéine recombinante Ag18070
• Nom complet: thyroglobulin
• Masse moléculaire calculée: 2768 aa, 305 kDa
• Numéro d’acquisition GenBank: BC140933
• Symbole du gène: Thyroglobulin
• Identification du gène (NCBI): 7038
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.

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