Anticorps Recombinant de lapin anti-Tie-2/CD202b

Tie-2/CD202b Recombinant Antibody for IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241753F12

N° de cat : 84469-5-PBS

Synonymes

241753F12, Angiopoietin-1 receptor, CD202b, EC:2.7.10.1, Endothelial tyrosine kinase

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Galerie de données de validation

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  IF Staining of bEnd.3 using 84469-5-RR (same clone as 84469-5-PBS)

  Immunofluorescent analysis of (4% PFA) fixed bEnd.3 cells using Tie-2 antibody (84469-5-RR, Clone: 241753F12 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84469-5-PBS in a different storage buffer formulation.

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Informations sur le produit

84469-5-PBS cible Tie-2/CD202b dans les applications de IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Tie-2/CD202b Protéine recombinante Eg1514
• Nom complet: endothelial-specific receptor tyrosine kinase
• Masse moléculaire calculée: 126kDa
• Numéro d’acquisition GenBank: NM_001290549.1
• Symbole du gène: Tek
• Identification du gène (NCBI): 21687
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Tie-2, or TEK, is a receptor tyrosine kinase (RTK) specifically expressed in endothelial cells. It plays a crucial role in angiogenesis, forming new blood vessels, and maintaining vascular stability. Tie-2 is a member of the Tie receptor family, characterized by the presence of immunoglobulin and epidermal growth factor (EGF) homology domains. Tie-2 plays a significant role in several vascular diseases, including vascular malformations like venous malformations. It is also implicated in pathological vascular remodeling associated with tumor growth, where it is often overexpressed in tumor vessels.

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