Anticorps Recombinant de lapin anti-Tie-2/CD202b

Tie-2/CD202b Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

FITC Plus Fluorescent Dye

CloneNo.

241753F12

N° de cat : FITC-98219

Synonymes

241753F12, Angiopoietin-1 receptor, CD202b, EC:2.7.10.1, Endothelial tyrosine kinase

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Galerie de données de validation

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  FC experiment of bEnd.3 using FITC-98219

  1x10^6 bEnd.3 cells were surface stained with 0.25 ug FITC Plus Anti-Mouse Tie-2/CD202b Rabbit RecAb (FITC-98219, Clone:241753F12) (red), or 0.25 ug FITC Plus Rabbit IgG Isotype Control RecAb (FITC-98136, Clone: 240953C9) (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: cellules bEnd.3,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

FITC-98219 cible Tie-2/CD202b dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: endothelial-specific receptor tyrosine kinase
• Masse moléculaire calculée: 126kDa
• Numéro d’acquisition GenBank: NM_001290549.1
• Symbole du gène: Tek
• Identification du gène (NCBI): 21687
• Conjugaison: FITC Plus Fluorescent Dye
• Excitation/Emission maxima wavelengths: 495 nm / 524 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

Tie-2, also known as CD202b or TEK, is a receptor tyrosine kinase (RTK) specifically expressed in endothelial cells. It plays a crucial role in angiogenesis, forming new blood vessels, and maintaining vascular stability. Tie-2 is a member of the Tie receptor family, characterized by the presence of immunoglobulin and epidermal growth factor (EGF) homology domains. Tie-2 plays a significant role in several vascular diseases, including vascular malformations like venous malformations. It is also implicated in pathological vascular remodeling associated with tumor growth, where it is often overexpressed in tumor vessels.

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