Anticorps Recombinant de lapin anti-Tissue Factor/CD142

Tissue Factor/CD142 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

240784E2

N° de cat : 98104-1-PBS

Synonymes

CD142, Coagulation factor III, F3, Tissue factor, 240784E2

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Galerie de données de validation

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  FC experiment of human PBMCs using 98104-1-RR (same clone as 98104-1-PBS)

  1x10^6 untreated or LPS-treated human PBMCs were surface stained with 0.25 ug Anti-Human Tissue Factor/CD142 Rabbit RecAb (98104-1-RR, Clone: 240784E2) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with APC Anti-Human CD14. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98104-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 98104-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98104-1-RR against Human Tissue Factor/CD142 were performed. The affinity constant is 0.834 nM.

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Informations sur le produit

98104-1-PBS cible Tissue Factor/CD142 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Tissue Factor/CD142 Protéine recombinante Eg1052
• Nom complet: coagulation factor III (thromboplastin, tissue factor)
• Masse moléculaire calculée: 33 kDa
• Numéro d’acquisition GenBank: NM_001993.5
• Symbole du gène: F3
• Identification du gène (NCBI): 2152
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

Normal blood coagulation is a complex process, involving a cascade of activation of different plasma proteins, ultimately resulting in the formation of a clot, called fibrin. Tissue Factor (TF), also named CD142, coagulation factor III or F3, is the primary initiator of the blood coagulation cascade and plays an essential role in hemostasis (PMID: 26877187; PMID: 33796108).

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