Anticorps Recombinant de lapin anti-Tissue Factor/CD142

Tissue Factor/CD142 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

240875G1

N° de cat : 98114-1-PBS

Synonymes

F3, Coagulation factor III, CD142, Tissue factor, TFA

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Galerie de données de validation

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  FC experiment of RAW 264.7 using 98114-1-RR (same clone as 98114-1-PBS)

  1x10^6 untreated or LPS-treated RAW 264.7 cells were surface stained with 0.25 ug Anti-Mouse Tissue Factor/CD142 Rabbit Recombinant Antibody (98114-1-RR, Clone: 240875G1) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98114-1-PBS in a different storage buffer formulation.

• 

  FC experiment of RAW 264.7 using 98114-1-RR (same clone as 98114-1-PBS)

  1x10^6 LPS-treated RAW 264.7 cells were surface stained with 0.25 ug Anti-Mouse Tissue Factor/CD142 Rabbit Recombinant Antibody (98114-1-RR, Clone: 240875G1) (red) or Isotype Control (blue) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). 1x10^6 untreated RAW 264.7 cells were surface stained with 0.25 ug Anti-Mouse Tissue Factor/CD142 Rabbit Recombinant Antibody (98114-1-RR, Clone: 240875G1) (black, dashed) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98114-1-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 98114-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98114-1-RR against Mouse Tissue Factor/CD142 were performed. The affinity constant is 0.442 nM.

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Informations sur le produit

98114-1-PBS cible Tissue Factor/CD142 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: coagulation factor III
• Masse moléculaire calculée: 33kDa
• Symbole du gène: Tissue Factor
• Identification du gène (NCBI): 14066
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

Normal blood coagulation is a complex process, involving a cascade of activation of different plasma proteins, ultimately resulting in the formation of a clot, called fibrin. Tissue Factor (TF), also named CD142, coagulation factor III or F3, is the primary initiator of the blood coagulation cascade and plays an essential role in hemostasis (PMID: 26877187; PMID: 33796108).

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