Anticorps Polyclonal de lapin anti-Toca 1

Toca 1 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 55055-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of mouse brain using 55055-1-AP (same clone as 55055-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 55055-1-AP (Toca 1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55055-1-PBS in a different storage buffer formulation.

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Informations sur le produit

55055-1-PBS cible Toca 1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: formin binding protein 1-like
• Masse moléculaire calculée: 70 kDa
• Poids moléculaire observé: 63-75 kDa
• Numéro d’acquisition GenBank: NM_017737
• Symbole du gène: Toca 1
• Identification du gène (NCBI): 54874
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Toca-1, also named as FNBP1L or C1orf39, belongs to the FNBP1 family. It is required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Toca-1 may bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. The antibody is specific to Toca-1.

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