Anticorps Recombinant de lapin anti-TrkB

TrkB Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250617A8

N° de cat : 85971-3-PBS

Synonymes

BDNF/NT-3 growth factors receptor, EC:2.7.10.1, GP145-TrkB/GP95-TrkB, Neurotrophic tyrosine kinase receptor type 2, Ntrk2

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Galerie de données de validation

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  WB analysis of mouse brain using 85971-3-RR (same clone as 85971-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85971-3-RR (TrkB antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85971-3-PBS in a different storage buffer formulation.

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Informations sur le produit

85971-3-PBS cible TrkB dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons rat, souris

• Réactivité: rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: TrkB Protéine recombinante Eg3000
• Nom complet: neurotrophic tyrosine kinase, receptor, type 2
• Masse moléculaire calculée: 92 kDa
• Poids moléculaire observé: 90-95 kDa, 140-145 kDa
• Numéro d’acquisition GenBank: NM_001025074.3
• Symbole du gène: Ntrk2
• Identification du gène (NCBI): 18212
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Tropomyosin-related kinase B (TrkB) is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. It is a single-pass type 1 membrane protein consisting of three domains: an extracellular ligand binding domain, a transmembrane domain and an intracellular tyrosine kinase domain. TrkB is primarily expressed in the central and peripheral nervous systems. TrkB plays an important role in neural development and maintenance through regulating neuronal differentiation, proliferation, survival, migration, neurogenesis, and plasticity.

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