Anticorps Monoclonal anti-UBE2S

UBE2S Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

8C9E6

N° de cat : 66897-1-PBS

Synonymes

8C9E6, E2 EPF, E2EPF, E2-EPF, EC:2.3.2.23

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Galerie de données de validation

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  WB analysis of HEK-293 using 66897-1-Ig (same clone as 66897-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 66897-1-Ig (UBE2S antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66897-1-PBS in a different storage buffer formulation.

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  WB analysis of Jurkat using 66897-1-Ig (same clone as 66897-1-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 66897-1-Ig (UBE2S antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66897-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HEK-293 using 66897-1-Ig (same clone as 66897-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 66897-1-Ig (UBE2S antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66897-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66897-1-PBS cible UBE2S dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2b
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: UBE2S Protéine recombinante Ag5378
• Nom complet: ubiquitin-conjugating enzyme E2S
• Masse moléculaire calculée: 222 aa, 24 kDa
• Poids moléculaire observé: 28 kDa
• Numéro d’acquisition GenBank: BC066948
• Symbole du gène: UBE2S
• Identification du gène (NCBI): 27338
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

UBE2S(Ubiquitin-conjugating enzyme E2 S) is also named as E2EPF and belongs to the ubiquitin-conjugating enzyme family. It acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C) and a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Overexpression of UBE2S can increase tumor cell proliferation, invasion, and metastasis through the VHL-HIF pathway (PMID:16819549).

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