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Anticorps Monoclonal anti-UBP1

UBP1 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1B10H3

N° de cat : 67318-1-PBS

Synonymes

DKFZp686L1745, LBP 1a, LBP 1B, LBP1, LBP1A, LBP1B, Transcription factor LBP 1, UBP1, Upstream binding protein 1

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using UBP1 Monoclonal antibody (67318-1-Ig)

    WB analysis using 67318-1-Ig (same clone as 67318-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67318-1-Ig (UBP1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67318-1-PBS in a different storage buffer formulation.

Informations sur le produit

67318-1-PBS cible UBP1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Mouse / IgG1
Clonalité Monoclonal
Type Anticorps
Immunogène UBP1 Protéine recombinante Ag5010
Nom complet upstream binding protein 1 (LBP-1a)
Masse moléculaire calculée 60 kDa
Poids moléculaire observé 65-68 kDa
Numéro d’acquisition GenBankBC047235
Symbole du gène UBP1
Identification du gène (NCBI) 7342
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine G
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

UBP1, also known as Transcription factor LBP-1, is a 540 amino acid protein, which is expressed in adrenal tissue, JEG-3, NCI-H295A, Hep-G2 and HeLa cell lines. UBP1 localizes in nuclear and can be induced by HIV-1 infection of lymphocytes. UBP1 functions as a transcriptional activator in a promoter context-dependent manner and modulates the placental expression of CYP11A1. UBP1 is involved in regulation of the alpha-globin gene in erythroid cells and represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.

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