Anticorps Polyclonal de lapin anti-UBQLN4

UBQLN4 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 29413-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 29413-1-AP (same clone as 29413-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29413-1-AP (UBQLN4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29413-1-PBS in a different storage buffer formulation.

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  IHC staining of human cervical cancer using 29413-1-AP (same clone as 29413-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 29413-1-AP (UBQLN4 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29413-1-PBS in a different storage buffer formulation.

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  IHC staining of human cervical cancer using 29413-1-AP (same clone as 29413-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 29413-1-AP (UBQLN4 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29413-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human cervical cancer using 29413-1-AP (same clone as 29413-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 29413-1-AP (UBQLN4 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29413-1-PBS in a different storage buffer formulation.

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Informations sur le produit

29413-1-PBS cible UBQLN4 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: UBQLN4 Protéine recombinante Ag29658
• Nom complet: ubiquilin 4
• Masse moléculaire calculée: 601 aa, 64 kDa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: BC063841
• Symbole du gène: UBQLN4
• Identification du gène (NCBI): 56893
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Ubiquilins (UBQLNs) are important factors for cell proteostasis maintenance. UBQLNs are involved in the modulation of the cell cycle, as well as in apoptosis, membrane receptors regulation, DNA repair, epithelial-mesenchymal transition, and miRNA activities. Ubiquilin 4 (UBQLN4) is an important member of the ubiquitin-like protein family. UBQLN4 is overexpressed in aggressive tumors and inhibits homologous recombination, redirecting doublestrand break repair to nonhomologous end joining, resulting in increased genome instability and inducing carcinogenesis.

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