Anticorps Polyclonal de lapin anti-UBR2

UBR2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 18853-1-PBS

Synonymes

N recognin 2, KIAA0349, EC:2.3.2.27, E3 ubiquitin-protein ligase UBR2, C6orf133

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Galerie de données de validation

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  WB analysis of BxPC-3 using 18853-1-AP (same clone as 18853-1-PBS)

  BxPC-3 cells were subjected to SDS PAGE followed by western blot with 18853-1-AP (UBR2 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18853-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse heart using 18853-1-AP (same clone as 18853-1-PBS)

  mouse heart tissue were subjected to SDS PAGE followed by western blot with 18853-1-AP (UBR2 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18853-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse cerebellum using 18853-1-AP (same clone as 18853-1-PBS)

  mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with 18853-1-AP (UBR2 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18853-1-PBS in a different storage buffer formulation.

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Informations sur le produit

18853-1-PBS cible UBR2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: UBR2 Protéine recombinante Ag13446
• Nom complet: ubiquitin protein ligase E3 component n-recognin 2
• Masse moléculaire calculée: 439aa,50 kDa; 1755aa,201 kDa
• Poids moléculaire observé: 60-66 kDa
• Numéro d’acquisition GenBank: BC064512
• Symbole du gène: UBR2
• Identification du gène (NCBI): 23304
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

UBR2(Ubiquitin-protein ligase E3-alpha-2) is also named as C6orf133, KIAA0349 and N-recognin-2. It is a component of the N-end rule pathway and recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. It has four isoforms produced by alternative splicing.

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