Anticorps Recombinant de lapin anti-Urocortin

Urocortin Recombinant Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241183B12

N° de cat : 84380-1-PBS

Synonymes

UCN, UROC, UI, 241183B12

---

Galerie de données de validation

• 

  WB analysis using 84380-1-RR (same clone as 84380-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84380-1-RR (UCN antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84380-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 84380-1-RR (same clone as 84380-1-PBS)

  Rat kidney tissue were subjected to SDS PAGE followed by western blot with 84380-1-RR (UCN antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84380-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse heart using 84380-1-RR (same clone as 84380-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 84380-1-RR (Urocortin antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84380-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse heart using 84380-1-RR (same clone as 84380-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 84380-1-RR (Urocortin antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84380-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

84380-1-PBS cible Urocortin dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: urocortin
• Masse moléculaire calculée: 13 kDa
• Poids moléculaire observé: 22 kDa
• Numéro d’acquisition GenBank: NM_003353
• Symbole du gène: UCN
• Identification du gène (NCBI): 7349
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Urocortin is a member of the sauvagine/corticotropin-releasing factor/urotensin I family that includes CRF, urotensin I, sauvagine, urocortin II and urocortin III. Urocortin is a potent anorexigenic peptide that induces fed-like motor activity when administered centrally or peripherally in fasted animals. Urocortin is also a potent and long-lasting hypotensive agent and increases coronary blood flow. Urocortin acts in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH) and binds with high affinity to CRF receptor types 1, 2-alpha, and 2-beta. Urocortin is synthesized as precursor, which is subsequently processed to the mature biologically active peptide (a 40-amino acid Molecule ). The 22 kDa may be a urocortin 1 precursor protein (PMID: 28887029).

{{ptg:RelatedPrimaryAntibodies}}