Anticorps Polyclonal de lapin anti-UGT3A1

UGT3A1 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17268-1-PBS

Synonymes

EC:2.4.1.17, UDP-glucuronosyltransferase 3A1, UDPGT 3A1

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Galerie de données de validation

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  WB analysis using 17268-1-AP (same clone as 17268-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17268-1-AP (UGT3A1 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17268-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17268-1-PBS cible UGT3A1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: UGT3A1 Protéine recombinante Ag11020
• Nom complet: UDP glycosyltransferase 3 family, polypeptide A1
• Masse moléculaire calculée: 59 kDa
• Poids moléculaire observé: 53 kDa
• Numéro d’acquisition GenBank: BC035012
• Symbole du gène: UGT3A1
• Identification du gène (NCBI): 133688
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

UGT3A1 (UDP Glycosyltransferase Family 3 Member A1) belongs to UDP-Glucuronosyltransferases (UGTs) superfamily. UGTs are membrane-bound enzymes localized at the subcellular level in the endoplasmic reticulum (ER) with an active site facing the lumenal side of the ER membrane. The genetic variation in UGT enzymes can modulate its regulation and expression, influencing UGT activity and resulting in pharmacological and physiologic effects. UGT3 family enzymes (UGT3A1 and UGT3A2) are expressed in the thymus, testis, and kidney, with a potential role in the metabolism of ursodeoxycholic acid during the treatment of cholestasis or gallstones.

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