Anticorps Polyclonal de lapin anti-UGT8

• Phare
• Validé par KD/KO

UGT8 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17982-1-PBS

Synonymes

UGT 8, UDP-galactose-ceramide galactosyltransferase, EC:2.4.1.47, CGT, Ceramide UDP-galactosyltransferase

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Galerie de données de validation

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  WB analysis of rat brain using 17982-1-AP (same clone as 17982-1-PBS)

  rat brain tissue were subjected to SDS PAGE followed by western blot with 17982-1-AP (UGT8 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17982-1-PBS in a different storage buffer formulation.

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  WB analysis of rat brain using 17982-1-AP (same clone as 17982-1-PBS)

  rat brain tissue were subjected to SDS PAGE followed by western blot with 17982-1-AP (UGT8 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17982-1-PBS in a different storage buffer formulation.

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  IP experiment of rat brain using 17982-1-AP (same clone as 17982-1-PBS)

  IP result of anti-UGT8 (IP:17982-1-AP, 4ug; Detection:17982-1-AP 1:1000) with rat brain tissue lysate 4000ug. This data was developed using the same antibody clone with 17982-1-PBS in a different storage buffer formulation.

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  IHC staining of human brain using 17982-1-AP (same clone as 17982-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain using 17982-1-AP (UGT8 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 17982-1-PBS in a different storage buffer formulation.

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  IHC staining of human brain using 17982-1-AP (same clone as 17982-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain using 17982-1-AP (UGT8 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 17982-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 17982-1-AP (same clone as 17982-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 17982-1-AP (UGT8 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 17982-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 17982-1-AP (same clone as 17982-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 17982-1-AP (UGT8 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 17982-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17982-1-PBS cible UGT8 dans les applications de WB, IHC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: UGT8 Protéine recombinante Ag12393
• Nom complet: UDP glycosyltransferase 8
• Masse moléculaire calculée: 541 aa, 61 kDa
• Poids moléculaire observé: 61 kDa
• Numéro d’acquisition GenBank: BC075069
• Symbole du gène: UGT8
• Identification du gène (NCBI): 7368
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

UGT8, also known as galacotosylceramide synthase or CGT (ceramide galactosyltransferase), is a key enzyme for galacotosylceramide (GalCer) biosynthesis. It is an ER transmembrane protein and has limited tissue distribution, with predominance in Schwann cells, oligodendrocytes, kidneys, testes, and intestine. UGT8 is highly enriched in myelin in the central nervous system. Its expression levels are strongly associated with histological typing in human oligodendrogliomas and astrocytomas; can be used as molecular marker to distinguish these tumors. Higher UGT8 levels had also been linked to metastatic properties of cancer cells. This antibody specifically recognizes the endogenous UGT8.

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