Anticorps Polyclonal de lapin anti-UNC5A-Specific

UNC5A-Specific Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 20239-1-PBS

Synonymes

KIAA1976, Netrin receptor UNC5A, Protein unc-5 homolog 1, Protein unc-5 homolog A, UNC5A

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Galerie de données de validation

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  WB analysis using 20239-1-AP (same clone as 20239-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 20239-1-AP (UNC5A-Specific antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20239-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse brain using 20239-1-AP (same clone as 20239-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 20239-1-AP (UNC5A-Specific antibody) at dilution of 1:100 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20239-1-PBS in a different storage buffer formulation.

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Informations sur le produit

20239-1-PBS cible UNC5A-Specific dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: unc-5 homolog A (C. elegans)
• Masse moléculaire calculée: 93 kDa
• Poids moléculaire observé: 103 kDa
• Numéro d’acquisition GenBank: NM_133369
• Symbole du gène: UNC5A
• Identification du gène (NCBI): 90249
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

UNC5A, also named as KIAA1976 and UNC5H1, belongs to the unc-5 family. It is a receptor for netrin required for axon guidance. It mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. The antibody is specific to UNC5A. It has no cross reaction to UNC5B, UNC5C and UNC5D.

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