Anticorps Recombinant de lapin anti-UNC5A-Specific

UNC5A-Specific Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

251526D11

N° de cat : 86582-1-PBS

Synonymes

KIAA1976, Netrin receptor UNC5A, Protein unc-5 homolog 1, Protein unc-5 homolog A, UNC5A

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Galerie de données de validation

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  WB analysis using 86582-1-RR (same clone as 86582-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86582-1-RR (UNC5A-Specific antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86582-1-PBS in a different storage buffer formulation.

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Informations sur le produit

86582-1-PBS cible UNC5A-Specific dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: unc-5 homolog A (C. elegans)
• Masse moléculaire calculée: 93 kDa
• Poids moléculaire observé: 103 kDa
• Numéro d’acquisition GenBank: NM_133369
• Symbole du gène: UNC5A
• Identification du gène (NCBI): 90249
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

UNC5A, also named as KIAA1976 and UNC5H1, belongs to the unc-5 family. It is a receptor for netrin required for axon guidance. It mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.

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