Anticorps Polyclonal de lapin anti-UNC5C-Specific

UNC5C-Specific Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 20240-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 20240-1-AP (same clone as 20240-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 20240-1-AP (UNC5C-Specific antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20240-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse brain using 20240-1-AP (same clone as 20240-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 20240-1-AP (UNC5C-Specific antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20240-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 20240-1-AP (same clone as 20240-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 20240-1-AP (UNC5C-Specific antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20240-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 20240-1-AP (same clone as 20240-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 20240-1-AP (UNC5C-Specific antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20240-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 20240-1-AP (same clone as 20240-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 20240-1-AP (UNC5C-Specific antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20240-1-PBS in a different storage buffer formulation.

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Informations sur le produit

20240-1-PBS cible UNC5C-Specific dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: unc-5 homolog C (C. elegans)
• Masse moléculaire calculée: 103 kDa
• Poids moléculaire observé: 50 kDa, 103 kDa
• Numéro d’acquisition GenBank: NM_003728
• Symbole du gène: UNC5C
• Identification du gène (NCBI): 8633
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

UNC5C, also named as UNC5H3, belongs to the unc-5 family. It is a receptor for netrin required for axon guidance. It mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. The antibody is specific to UNC5C.

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