Anticorps Recombinant de lapin anti-UNC79

UNC79 Recombinant Antibody for IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241628A7

N° de cat : 84642-1-PBS

Synonymes

Protein unc-79 homolog, KIAA1409, 241628A7

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Galerie de données de validation

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  IHC staining of mouse brain using 84642-1-RR (same clone as 84642-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 84642-1-RR (UNC79 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84642-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 84642-1-RR (same clone as 84642-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 84642-1-RR (UNC79 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84642-1-PBS in a different storage buffer formulation.

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  IF Staining of SH-SY5Y using 84642-1-RR (same clone as 84642-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed SH-SY5Y cells using UNC79 antibody (84642-1-RR, Clone: 241628A7 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84642-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84642-1-RR

  Biolayer interferometry (BLl) kinetic assays of 84642-1-RR against Human UNC79 were performed. The affinity constant is 11 nM.

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Informations sur le produit

84642-1-PBS cible UNC79 dans les applications de IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: UNC79 Protéine recombinante Ag35440
• Nom complet: KIAA1409
• Masse moléculaire calculée: 295 kDa
• Numéro d’acquisition GenBank: NM_020818.4
• Symbole du gène: UNC79
• Identification du gène (NCBI): 57578
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

UNC79 is one of the key auxiliary subunits of the NALCN channel complex. Together with NALCN, FAM155A, and UNC80, it constitutes the NALCN channel body and is essential for maintaining neuronal excitability, motor function, pain sensitivity, and circadian rhythm (PMID: 35387979).

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