Anticorps Polyclonal de lapin anti-UPK1A

UPK1A Polyclonal Antibody for IHC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

IHC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 25275-1-PBS

Synonymes

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Galerie de données de validation

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  IP experiment of mouse bladder using 25275-1-AP (same clone as 25275-1-PBS)

  IP result of anti-UPK1A (IP:25275-1-AP, 4ug; Detection:25275-1-AP 1:300) with mouse bladder tissue lysate 3200ug. This data was developed using the same antibody clone with 25275-1-PBS in a different storage buffer formulation.

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  IHC staining of human bladder using 25275-1-AP (same clone as 25275-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human bladder tissue slide using 25275-1-AP (UPK1A antibody) at dilution of 1:5000 (under 10x lens).. This data was developed using the same antibody clone with 25275-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human bladder using 25275-1-AP (same clone as 25275-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human bladder tissue slide using 25275-1-AP (UPK1A antibody) at dilution of 1:5000 (under 40x lens).. This data was developed using the same antibody clone with 25275-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse bladder using 25275-1-AP (same clone as 25275-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse bladder tissue slide using 25275-1-AP (UPK1A antibody) at dilution of 1:16000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25275-1-PBS in a different storage buffer formulation.

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  IHC staining of rat bladder using 25275-1-AP (same clone as 25275-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat bladder tissue slide using 25275-1-AP (UPK1A antibody) at dilution of 1:16000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25275-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse bladder using 25275-1-AP (same clone as 25275-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse bladder tissue slide using 25275-1-AP (UPK1A antibody) at dilution of 1:16000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25275-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat bladder using 25275-1-AP (same clone as 25275-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat bladder tissue slide using 25275-1-AP (UPK1A antibody) at dilution of 1:16000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25275-1-PBS in a different storage buffer formulation.

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Informations sur le produit

25275-1-PBS cible UPK1A dans les applications de IHC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: UPK1A Protéine recombinante Ag17356
• Nom complet: uroplakin 1A
• Masse moléculaire calculée: 258 aa, 29 kDa
• Poids moléculaire observé: 29 kDa
• Numéro d’acquisition GenBank: BC107098
• Symbole du gène: UPK1A
• Identification du gène (NCBI): 11045
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Uroplakins are a group of urothelial differentiation-related membrane proteins. They are components of the asymmetric unit membrane (AUM), which forms the apical plaques of mammalian urothelium and is believed to play a role in strengthening the urothelial apical surface thus preventing the cells from rupturing during bladder distention (PMID: 8175808). Uroplakin-1a (UPK1A) belongs to the tetraspanin (TM4SF) family. UPK1A plays an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane.

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