Anticorps Recombinant de lapin anti-UPK1A

UPK1A Recombinant Antibody for WB, IF-P, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IF-P, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

251472C10

N° de cat : 86799-1-PBS

Synonymes

TSPAN21, Tetraspanin-21, Tspan-21, UP1a, UPIa

---

Galerie de données de validation

• 

  WB analysis using 86799-1-RR (same clone as 86799-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86799-1-RR (UPK1A antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86799-1-PBS in a different storage buffer formulation.

• 

  IF Staining of mouse bladder using 86799-1-RR (same clone as 86799-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse bladder tissue using UPK1A antibody (86799-1-RR, Clone: 251472C10 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 86799-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

86799-1-PBS cible UPK1A dans les applications de WB, IF-P, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: UPK1A Protéine recombinante Ag17356
• Nom complet: uroplakin 1A
• Masse moléculaire calculée: 258 aa, 29 kDa
• Poids moléculaire observé: 29 kDa
• Numéro d’acquisition GenBank: BC107098
• Symbole du gène: UPK1A
• Identification du gène (NCBI): 11045
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Uroplakins are a group of urothelial differentiation-related membrane proteins. They are components of the asymmetric unit membrane (AUM), which forms the apical plaques of mammalian urothelium and is believed to play a role in strengthening the urothelial apical surface thus preventing the cells from rupturing during bladder distention (PMID: 8175808). Uroplakin-1a (UPK1A) belongs to the tetraspanin (TM4SF) family. UPK1A plays an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane.

{{ptg:RelatedPrimaryAntibodies}}