Anticorps Recombinant de lapin anti-UQCRC1

• Phare
• Validé par KD/KO

UQCRC1 Recombinant Antibody for WB, IHC, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, ELISA

Conjugaison

Non conjugué

CloneNo.

240507A6

N° de cat : 83671-2-PBS

Synonymes

240507A6, Complex III subunit 1, Core protein I, Cytochrome b-c1 complex subunit 1, mitochondrial, D3S3191

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Galerie de données de validation

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  WB analysis using 83671-2-RR (same clone as 83671-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83671-2-RR (UQCRC1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83671-2-PBS in a different storage buffer formulation.

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  WB analysis of HeLa using 83671-2-RR (same clone as 83671-2-PBS)

  WB result of UQCRC1 antibody (83671-2-RR; 1:20000; incubated at room temperature for 1.5 hours) with sh-Control and sh-UQCRC1 transfected HeLa cells. This data was developed using the same antibody clone with 83671-2-PBS in a different storage buffer formulation.

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  IHC staining of human stomach cancer using 83671-2-RR (same clone as 83671-2-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 83671-2-RR (UQCRC1 antibody) at dilution of 1:2000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer(pH9). This data was developed using the same antibody clone with 83671-2-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83671-2-RR

  Biolayer interferometry (BLl) kinetic assays of 83671-2-RR against Human UQCRC1 were performed. The affinity constant is 0.294 nM.

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Informations sur le produit

83671-2-PBS cible UQCRC1 dans les applications de WB, IHC, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: UQCRC1 Protéine recombinante Ag16322
• Nom complet: ubiquinol-cytochrome c reductase core protein I
• Masse moléculaire calculée: 480 aa, 53 kDa
• Poids moléculaire observé: 45 kDa
• Numéro d’acquisition GenBank: BC009586
• Symbole du gène: UQCRC1
• Identification du gène (NCBI): 7384
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

UQCRC1(Cytochrome b-c1 complex subunit 1, mitochondrial), also named as QCR1 and UQCR1, is a ubunit of the cytochrome bc1 complex (complex III) of the mitochondrial respiratory chain, may mediate the formation of the complex between cytochromes c and c1. The gene encodes a 53 kDa protein with a 34 amino acids transit peptide. It is associated with apoptosis or inhibition of cancer cell growth.

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