Anticorps Polyclonal de lapin anti-URAT1

• Phare
• Validé par KD/KO

URAT1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, porc, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 14937-1-PBS

Synonymes

SLC22A12, RST, Renal-specific transporter, Renal specific transporter, Organic anion transporter 4-like protein

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Galerie de données de validation

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  WB analysis using 14937-1-AP (same clone as 14937-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 14937-1-AP (URAT1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14937-1-PBS in a different storage buffer formulation.

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  WB analysis of pig kidney using 14937-1-AP (same clone as 14937-1-PBS)

  pig kidney tissue were subjected to SDS PAGE followed by western blot with 14937-1-AP (URAT1 Antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14937-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 14937-1-AP (same clone as 14937-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 14937-1-AP (URAT1 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14937-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 14937-1-AP (same clone as 14937-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 14937-1-AP (URAT1 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14937-1-PBS in a different storage buffer formulation.

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Informations sur le produit

14937-1-PBS cible URAT1 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, porc, rat, souris

• Réactivité: Humain, porc, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: URAT1 Protéine recombinante Ag6770
• Nom complet: solute carrier family 22 (organic anion/urate transporter), member 12
• Masse moléculaire calculée: 60 kDa
• Poids moléculaire observé: 65-70 kDa, 40 kDa
• Numéro d’acquisition GenBank: BC053348
• Symbole du gène: URAT1
• Identification du gène (NCBI): 116085
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Human urate anion exchanger (URAT1), also known as SLC22A12, is a urate transporter located in the proximal tubules of human kidney and responsible for urate reabsorption. Defects in gene encoding URAT1 cause hypouricemia renal type 1 (RHUC1). This antibody recognizes the native and glycosylated URAT1 between 65 and 70 kDa as well as the truncated 40kDa protein.

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