Anticorps Monoclonal anti-USP22

USP22 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

3D11H9

N° de cat : 60905-1-PBS

Synonymes

Deubiquitinating enzyme 22, EC:3.4.19.12, KIAA1063, Ubiquitin carboxyl-terminal hydrolase 22, Ubiquitin thioesterase 22

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Galerie de données de validation

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  WB analysis using 60905-1-Ig (same clone as 60905-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 60905-1-Ig (USP22 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60905-1-PBS in a different storage buffer formulation.

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Informations sur le produit

60905-1-PBS cible USP22 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: USP22 Protéine recombinante Ag34933
• Nom complet: ubiquitin specific peptidase 22
• Masse moléculaire calculée: 60 kDa
• Poids moléculaire observé: 58 kDa
• Numéro d’acquisition GenBank: NM_015276
• Symbole du gène: USP22
• Identification du gène (NCBI): 23326
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

USP22, also named as KIAA1063 and USP3L, belongs to the peptidase C19 family and UBP8 subfamily. It is histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. USP22 catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. It is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. USP22 is required for nuclear receptor-mediated transactivation and cell cycle progression. USP22 has 2 isoforms with molecular mass of 58kDa and 60 kDa. The antibody is specific to USP22.

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