Anticorps Recombinant de lapin anti-USP48

USP48 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

251394C2

N° de cat : 86523-1-PBS

Synonymes

Deubiquitinating enzyme 48, EC:3.4.19.12, RAP1GA1, Ubiquitin carboxyl-terminal hydrolase 48, Ubiquitin thiolesterase 48

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Galerie de données de validation

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  WB analysis using 86523-1-RR (same clone as 86523-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86523-1-RR (USP48 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86523-1-PBS in a different storage buffer formulation.

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Informations sur le produit

86523-1-PBS cible USP48 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: USP48 Protéine recombinante Ag2749
• Nom complet: ubiquitin specific peptidase 48
• Masse moléculaire calculée: 1035 aa, 119 kDa
• Poids moléculaire observé: 120 kDa
• Numéro d’acquisition GenBank: BC013567
• Symbole du gène: USP48
• Identification du gène (NCBI): 84196
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

USP48 (Ubiquitin Specific Peptidase 48) is a deubiquitinating enzyme and a member of the Ubiquitin Specific Protease (USP) family. This protein specifically recognizes and cleaves ubiquitin chains on substrate proteins, reversing the ubiquitination process, thereby regulating the stability, activity, and subcellular localization of target proteins. USP48 plays a key role in various cellular processes, including DNA damage repair, cell cycle regulation, and gene transcription. Studies have shown that USP48 is closely related to pathological processes such as cancer and neurodegenerative diseases, for example, by stabilizing transcription factors or signaling pathway proteins to influence tumor development.

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