Anticorps Polyclonal de lapin anti-UTP23

UTP23 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 15950-1-PBS

Synonymes

rRNA-processing protein UTP23 homolog, C8orf53

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Galerie de données de validation

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  WB analysis of mouse liver using 15950-1-AP (same clone as 15950-1-PBS)

  mouse liver tissue were subjected to SDS PAGE followed by western blot with 15950-1-AP (UTP23 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15950-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse liver using 15950-1-AP (same clone as 15950-1-PBS)

  mouse liver tissue were subjected to SDS PAGE followed by western blot with 15950-1-AP (UTP23 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15950-1-PBS in a different storage buffer formulation.

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Informations sur le produit

15950-1-PBS cible UTP23 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: UTP23 Protéine recombinante Ag8609
• Nom complet: UTP23, small subunit (SSU) processome component, homolog (yeast)
• Masse moléculaire calculée: 249 aa, 28 kDa
• Poids moléculaire observé: 28 kDa, 17 kDa
• Numéro d’acquisition GenBank: BC005955
• Symbole du gène: UTP23
• Identification du gène (NCBI): 84294
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

UTP23 is a component of ribosomal small-subunit processome, which is involved in ribosome synthesis and RNA maturation. UTP23 contains a long and likely unstructured tail at the C terminus of the PIN domain (PMID: 24152547). UTP23 is a target of genetic variation associated with colorectal cancer in chromosome 8q23.3, and it may coordinate with EIF3H in this region in the development of colorectal cancer. Low expression of UTP23 predicts poorer prognosis of ovarian cancer patients (PMID: 31540773, 37880005). It has 2 predicted molecular weight of 28 kDa and 17 kDa.

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